COVID-19 disrupted both in-person learning and routine well-child visits for many children during the last year. We all want our kids to be back in school safely, and that means getting caught up on vaccines that were missed during the past year. The Centers for Disease Control and Prevention’s (CDC) public sector vaccine ordering data show a 14% drop in childhood vaccines for the period of the 2020-2021 school year compared to the 2018-2019 school year, and measles vaccine is down by more than 20%. Catch-up vaccination will require efforts from healthcare systems, healthcare providers, schools, state and local governments, and families.